We are seeking a motivated colleague to fill in the open position of a Ph.D. student in SONATA BIS project funded by National Science Center Poland. The position will be available as of October 1st, 2019. The successful candidate will study mechanisms governing the transport of ligands in enzymes using the cutting-edge methods like MSM modeling, adaptive and enhanced sampling simulations. The research will also include the component of a method development. The acquired results will be crucial for discoveries of the molecular origins of transport-related pathologies, improvements of binding kinetics of inhibitors, and engineering of improved biocatalysts. The laboratory is located in Poznan, Poland, and is jointly affiliated to the International Institute of Molecular and Cell Biology in Warsaw and the Institute of Molecular Biology and Biotechnology, Faculty of Biology, Adam Mickiewicz University in Poznan – both rank among the top research institutes in Poland.